PROFESSIONAL EXPERIENCE
9/1/98-PRESENT President and CEO, Mitotyping Technologies, LLC, 2565 Park Center Boulevard, Suite 200, State College, PA 16801

2000-2004 Editorial Board, Journal of Forensic Sciences

10/1/99-PRESENT Affiliate Researcher, Dept. of Anthropology, The Pennsylvania State University

9/97-9/98 Senior Research Assistant, Dept. of Anthropology, The Pennsylvania State University

9/96-7/97 Visiting Postdoctoral Researcher, Cellular Genetics, Institute of Molecular Medicine, University of Oxford, Oxford, UK

5/94-10/94 Research Assistant, Dept. of Anthropology, The Pennsylvania State University

1/93-5/93 Research Assistant, Intercollege Graduate Program in Genetics, The Pennsylvania State University

8/92-12/92 Teaching Assistant, Introductory Biological Anthropology, The Pennsylvania State University

10/78-8/81 Physician Assistant, Department of Pediatrics, University of Virginia Medical Center

7/77-4/78 Physician Assistant, Blue Ridge General Practice, Lynchburg, VA

EDUCATION
8/91-3/96 PhD, Genetics, The Pennsylvania State University, University Park, PA, Adviser, Dr. Mark Stoneking, Department of Anthropology

1/89-8/91 MS, Genetics, The Pennsylvania State University, University Park, PA, Adviser, Dr. Robert B. Eckhardt, Department of Anthropology

8/75-8/77 Physician Assistant Program, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC

8/72-8/77 BS, Wake Forest University, Winston-Salem, NC

PROFESSIONAL MEMBERSHIPS
• American Academy of Forensic Sciences
• American Association for the Advancement of Science
• Sigma Xi Scientific Research Society

REVIEWER
• Journal of Forensic Sciences
• American Journal of Human Genetics
• Forensic Science Reviews
• Forensic Science Communications
• Croatian Medical Journal
• Genomics
• Mitochondrion

PUBLICATIONS
Melton, T. Mitochondrial DNA heteroplasmy (submitted) Forensic Science Reviews. (invited paper).

Melton, T. and Weedn, V. (in press) Forensic DNA sequencing. In: Analytic Chemistry of DNA Sequencing, Brian Nunnally (ed.).

Melton, T. (2003) Forensic mitochondrial DNA analysis. In: McGraw-Hill Annual Review of Science and Technology. McGraw Hill, New York, p.140-143.

Owsley, D., Ellwood, B., and Melton, T. (in preparation) Search for the grave of William Preston Longley, hanged Texas gunfighter. Historial Archaeology.

Melton, T. (2002) Mitochondrial DNA: solving the mystery of Anna Anderson. In: Hard Evidence: Case Studies in Forensic Anthropology, D.W. Steadman (ed.).

Melton, T. and Nelson, K. (2001) Forensic mitochondrial DNA analysis: two years of commercial casework experience in the United States. Croatian Medical Journal 42:298-303.

Melton, T. Mitochondrial DNA: Solving the mystery of Anna Anderson. D.W. Steadman (ed.). In: Hard Evidence: Case studies in forensic anthropology, Prentice Hall, Upper Saddle River, New Jersey, p. 205-211.

Melton, T., Clifford, S., Kaiser, M., Nasidze, I., and Stoneking, M. (2001) Diversity and heterogeneity of mtDNA in North American populations. Journal of Forensic Sciences 46: 43-49.

Melton, T. and Sensabaugh, G. Mitochondrial DNA. (2000) In: Encyclopedia of Forensic Science, Academic Press Limited, London.

Melton, T. and Stoneking, M. SSO-probe hybridization analysis of mtDNA. In Mitochondrial DNA analysis in forensic science, A. Sajantila (ed.).

Melton, T., Batzer, M., Clifford, S., Martinson, J., and Stoneking, M. (1998) Evidence for the proto-Austronesian homeland in Asia: mitochondrial and nuclear DNA variation in Taiwanese aboriginal tribes. American Journal of Human Genetics 63:1807-1823.

Melton, T., Ginther, C., Sensabaugh, G., Soodyall, H., and Stoneking, M. (1997) The extent of heterogeneity in mitochondrial DNA of sub-Saharan African populations. Journal of Forensic Sciences 42:580-590

Melton, T., Wilson, M., Batzer, M., and Stoneking, M. (1997) Extent of heterogeneity in mitochondrial DNA of European populations. Journal of Forensic Sciences 42:437-446

Melton, T. and Stoneking, M. (1996) The extent of heterogeneity in mitochondrial DNA of ethnic Asian populations. Journal of Forensic Sciences 41:587-598

Melton, T. (1996) The influence of mitochondrial DNA variation on forensic DNA typing. PhD thesis, The Pennsylvania State University, University Park, PA

Melton, T., Peterson, R., Redd, A., Saha, N., Sofro, A.S.M., Martinson, J., and Stoneking, M. (1995) Polynesian genetic affinities with Southeast Asian populations as identified by mitochondrial DNA analysis. American Journal of Human Genetics 57:403-414

Gill, P., Kimpton, C., Aliston-Greiner, R., and Sullivan, K., Stoneking, M., Melton, T., Nott, J., Barritt, S., Roby, R., Holland, M., Weedn, V. (1995) Establishing the identity of Anna Anderson Manahan. Nature Genetics 9: 9-10

Eckhardt, R. B. and Melton, T. W., eds. (1992) Population Studies on Human Adaptation and Evolution in the Peruvian Andes, Number 14, Occasional Papers in Anthropology, Matson Museum of Anthropology, The Pennsylvania State University, University Park, PA., 268 pages

Melton, T. W. (1991) Comparison of Growth and Development in Two Peruvian Populations of High Altitude Ancestry. MS thesis, The Pennsylvania State University, University Park, PA

Wilson, T. A., Melton, T. W., and Clarke, W. L. (1983) The effect of fenfluramine and caloric restriction on carbohydrate homeostasis in patients with lipodystrophy. Diabetes Care 6:160

Clarke, W. L., Melton, T. W., and Bright, G. M. (1983). The effect of hyperglucagonemia on blood glucose concentrations and on insulin requirements during fasting in insulin dependent diabetes mellitus. Acta Endocrinologica 102: 557

Clarke, W., Melton, T., Sachse, M., Schneider, J., Schneider, K., and Yarbrough, M. (1980). Evaluation of a new reflectance photometer for use in home blood glucose monitoring. Diabetes Care 4: 547

Bright, G., Melton, T., Rogol, A., and Clarke, W. (1980). Failure of cortisol to inhibit early morning increases in basal insulin requirements in fasting insulin-dependent diabetics. Diabetes 29: 680

ABSTRACTS
Melton, T. and Nelson, K. (1999) Diversity of casework, heteroplasmy, and population variation: mtDNA analysis in the private sector. First International Conference and Exhibition on Forensic Human Identification, The Forensic Science Service, October 24-26, 1999, London.

Nelson, K. and Melton, T. (1999) Mitochondrial DNA testing: casework in the private sector, heteroplasmy, and genetic diversity within the United States. Tenth International Symposium on Human Identification, September 26-29, 1999, Orlando, FLA

Nelson, K. and Melton, T. (1999) Forensic applications of human mitochondrial DNA variation. Symposium on Human Diversity and Evolution, Penn State University, June 11-13, State College, PA

Melton, T., Clifford, S., Stoneking, M., (1998) Variation and geographic subpopulation heterogeneity in the mitochondrial DNA control region of North Americans. American Academy of Forensic Sciences, February 9-14, San Francisco, CA

Stoneking, M., and Melton, T. (1996) Forensic applications of mitochondrial DNA analysis. Cambridge Symposium on DNA Forensics, April 21-27, Sante Fe, NM

Clarke, W., Melton, T., Sachse, M., Schneider, J., Schneider M., and Yarbrough, M. (1981) Evaluation of a new reflectance photometer for use in home blood glucose monitoring. Diabetes 30 (Suppl. 1): 92

Wilson, T., Melton, T., and Clarke, W. (1980) The effect of fenfluramine on glucose homeostasis in lipodystrophy. Diabetes 29 (Suppl. 2): 498

Bright, G., Melton, T., Rogol, A., and Clarke, W. (1980) The effect of exogenous human growth hormone on blood glucose concentrations and insulin requirements during closed-loop (Biostator R-GCIIS) control of diabetes mellitus. Diabetes 29 (Suppl. 2): 483

Clarke, W., White, N., Melton, T., and Santiago, J. (1979). Diurnal variation in closed-loop insulin requirements in fasting insulin dependent diabetics: probable role of the adrenal pituitary axis. Workshop on Artificial Beta Cell, Budapest-Heviz (Hungary)

PRESENTATIONS
Melton, T. Mitochondrial DNA Forensic Analysis: How the Smallest Genome Convicts and Exonerates. 2003 Benedum Lecture Series, West Virginia University, October 16, 2003 (invited).

Melton, T. Human hair mtDNA analysis: success, size, and site heteroplasmy. The Third European-American School in Forensic Genetics and Mayo Clinic Course in Advanced Molecular and Cellular Medicine, Zagreb, Croatia, September 1-5, 2003 (invited).

Melton, T. Scientific developments and future applications of mitochondrial DNA analysis. Pennsylvania Supreme Court DNA Programs, State College, PA, March 19, 2003, and Plymouth Meeting, PA, March 26, 2003 (invited).

Melton, T. Hair. Panel Discussion, National Conference on Science and the Law, U.S. Department of Justice, Miami, FL, October 3-5, 2002 (invited).

Melton, T. Mitochondrial DNA typing. DNA Seminar, Ontario Provincial Police, Muskoka Sands, Ontario, September 8-13, 2002 (invited).

Melton, T. Ancient mtDNA analysis in forensic casework. Human Forensic Mitochondrial DNA Analysis Worksop, American Academy of Forensic Sciences Annual Meeting, Atlanta, GA, February 11, 2001 (invited).

Melton, T. Scientific developments and future expectations in mtDNA analysis. DNA Conference, Institute of Forensic Schience and the Law, Duquesne University, November 30-December 1, 2001 (invited).

Melton, T. Mitochondrial DNA typing. DNA Seminar, Florida Prosecuting Attorneys Association, Altamonte Spring, FL, August 23-24, 2001 (invited).

Melton, T. Working the toughest mitochondrial DNA case in the world: getting good data out of difficult evidence. American Academy of Forensic Sciences, February 19-24, 2001, Seattle, WA.

Melton, T. What mitochondrial DNA analysis can and cannot do in parentage testing. 11th International Symposium on Human Identification, October 10-13, 2000, Biloxi, MI (invited).

Melton, T. Diversity and heterogeneity in mitochondrial DNA of North American populations. Cambridge Healthtech Institute’s Fourth Annual DNA Forensics, May 31-June 2, 2000, Springfield, VA (invited).

Melton, T. Forensic mitochondrial DNA analysis: 2000 status. Fifth Annual Conference of the Future of DNA: Implications for the Criminal Justice System, May 8-9, 2000, New York (invited).

Melton, T., and Nelson, K. Beyond simple substitutions: Length variation and heteroplasmy in mtDNA forensic casework. American Academy of Forensic Sciences, February 21-26, 2000, Reno, NV.

Melton, T. Subpopulation heterogeneity in mtDNA variation. First International Conference on Forensic Human Identification in the Millenium, Mitochondrial Analysis Workshop, October 27-28, 1999, London (invited)

Melton, T. Forensic use of mitochondrial DNA 1998. California Association of Criminalists DNA Workshop, October 14, 1998, San Diego, CA (invited)

Melton, T. Forensic use of mitochondrial DNA 1998. IBC’s International Conference on DNA Forensic Analysis, July 30-31, 1998, Annapolis, MD (invited)

Melton, T. Forensic use of mitochondrial DNA 1998. The Annual Conference on Criminal Justice Research and Evaluation: Viewing Crime and Justice from a Collaborative Perspective, July 26-29, 1998, Washington, D.C. (invited)

Melton, T. Forensic use of mitochondrial DNA 1998. Third Annual Conference on the Future of DNA: Implications for the Criminal Justice System, May 21-22, 1998, Chicago, IL (invited)

Melton, T., Martinson, J., and Stoneking, M. Mitochondrial DNA variation in aboriginal peoples of Taiwan and comparison with Southeast Asian populations, Cultural and Genetic Affinities of Indigenous Peoples of Taiwan, Academia Sinica, May 21-23, 1996, Taipei, Taiwan, ROC (invited)

Melton, T., Ginther, C., Wilson, M., and Stoneking, M. The extent of subpopulation heterogeneity in mitochondrial DNA types of African and European populations. American Academy of Forensic Sciences, February 19-24, 1996, Nashville, TN

Melton, T. Mitochondrial DNA variation in the Mukogodo. American Anthropological Association, November 15-19, 1995, Washington, DC

Melton, T. and Stoneking, M. Subpopulation heterogeneity in mitochondrial DNA evaluated with analysis of molecular variance of sequence-specific oligonucleotide typing of worldwide populations. Sixth International Symposium on Human Identification, October 12-14, 1995, Scottsdale, AZ

Melton, T., Martinson, J., Saha, Sofro A., N., and Stoneking, M. The extent of subpopulation heterogeneity in mitochondrial DNA types in ethnic Asian populations. American Academy of Forensic Sciences, February 14-18, 1995, Seattle, WA

Melton, T., Peterson, R., Redd., A., Sofro, A., Soodyall, H., and Stoneking, M. Polynesian origins: The mitochondrial DNA 9-bp deletion marker and associated control region haplotypes in southeast Asian populations. Poster Exhibit, Society for Molecular Biology and Evolution, June 15-19, 1994, Athens, GA

Melton, T. Subpopulation heterogeneity in mitochondrial DNA for ethnic Asian populations. Technical Working Group on DNA Analysis Methods, July 26, 1993, and July 25, 1994, FBI Academy, Quantico, VA

Kumar, S. and Melton, T. Phylogenetic trees from molecular data: construction and applications. Graduate Research Exhibition, The Pennsylvania State University, March 20-21, 1992, University Park, PA

Melton, T.W., and Eckhardt, R.B., Thoracic development at high and low altitude provides confirmatory evidence for the existence of genetic factors influencing adaptation to high altitude in South America, Poster exhibit, Human Biology Council, April 2-6, 1991, Milwaukee,WI

Melton, T. Genetic adaptation in the Andes. Graduate Research Exhibition, The Pennsylvania State University, March 22-23, 1991, University Park, PA